Sylvatic Dengue Viruses Share the Pathogenic Potential of Urban/Endemic Dengue Viruses

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Sylvatic dengue viruses share the pathogenic potential of urban/endemic dengue viruses.

Dengue virus (DENV) exists in both sylvatic and urban/ endemic ecotypes (15), and the potential for emergence of sylvatic strains has become a focus of research. Recently Mota and Rico-Hesse (10) attempted to evaluate the pathogenic potential of viruses belonging to different genetic subgroups of DENV serotype 2 (DENV-2). Based on the viremia levels and erythema index profiles of one sylvatic g...

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Dengue viruses (DENV) are the most important arboviral pathogens in tropical and subtropical regions throughout the world. DENV transmission includes both a sylvatic, enzootic cycle between nonhuman primates and arboreal mosquitoes of the genus Aedes, and an urban, endemic/epidemic cycle between Aedes aegypti, a mosquito with larval development in peridomestic water containers, and human reserv...

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Endemic/epidemic dengue viruses (DEN) that are transmitted among humans by the mosquito vectors Aedes aegypti and Aedes albopictus are hypothesized to have evolved from sylvatic DEN strains that are transmitted among nonhuman primates in West Africa and Malaysia by other Aedes mosquitoes. We tested this hypothesis with phylogenetic studies using envelope protein gene sequences of both endemic/e...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2010

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.02640-09